Age- and Light-Dependent Development of Localised Retinal Atrophy in CCL2(−/−)CX3CR1(GFP/GFP) Mice

Previous studies have shown that CCL2/CX3CR1 deficient mice on C57BL/6N background (with rd8 mutation) have an early onset (6 weeks) of spontaneous retinal degeneration. In this study, we generated CCL2(−/−)CX3CR1(GFP/GFP) mice on the C57BL/6J background. Retinal degeneration was not detected in CCL...

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Detalhes bibliográficos
Main Authors: Chen, Mei, Hombrebueno, Jose R., Luo, Chang, Penalva, Rosana, Zhao, Jiawu, Colhoun, Liza, Pandi, Sudha Pirya Soundara, Forrester, John V., Xu, Heping
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3630229/
https://ncbi.nlm.nih.gov/pubmed/23637822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061381
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