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Phosphorylation of the Retinoic Acid Receptor Alpha Induces a Mechanical Allosteric Regulation and Changes in Internal Dynamics

Nuclear receptor proteins constitute a superfamily of proteins that function as ligand dependent transcription factors. They are implicated in the transcriptional cascades underlying many physiological phenomena, such as embryogenesis, cell growth and differentiation, and apoptosis, making them one...

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Hlavní autoři: Chebaro, Yassmine, Amal, Ismail, Rochel, Natacha, Rochette-Egly, Cécile, Stote, Roland H., Dejaegere, Annick
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3630199/
https://ncbi.nlm.nih.gov/pubmed/23637584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003012
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