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Baseline Gene Expression Signatures in Monocytes from Multiple Sclerosis Patients Treated with Interferon-beta

BACKGROUND: A relatively large proportion of relapsing-remitting multiple sclerosis (RRMS) patients do not respond to interferon-beta (IFNb) treatment. In previous studies with peripheral blood mononuclear cells (PBMC), we identified a subgroup of IFNb non-responders that was characterized by a base...

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Detalhes bibliográficos
Main Authors: Bustamante, Marta F., Nurtdinov, Ramil N., Río, Jordi, Montalban, Xavier, Comabella, Manuel
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3630153/
https://ncbi.nlm.nih.gov/pubmed/23637780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060994
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