Bovine HEXIM1 inhibits bovine immunodeficiency virus replication through regulating BTat-mediated transactivation

The bovine immunodeficiency virus (BIV) transactivator (BTat) recruits the bovine cyclin T1 (B-cyclin T1) to the LTR to facilitate the transcription of BIV. Here, we demonstrate that bovine hexamethylene bisacetamide (HMBA)-induced protein 1 (BHEXIM1) inhibits BTat-mediated BIV LTR transcription. Th...

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Bibliografske podrobnosti
Main Authors: Guo, Hong-yan, Ma, Yong-gang, Gai, Yuan-ming, Liang, Zhi-bin, Ma, Jing, Su, Yang, Zhang, Qi-cheng, Chen, Qi-min, Tan, Juan
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2013
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3630055/
https://ncbi.nlm.nih.gov/pubmed/23537346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1297-9716-44-21
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