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Genome-Wide Somatic Copy Number Alterations in Low-Grade PanINs and IPMNs from Individuals with a Family History of Pancreatic Cancer

PURPOSE: Characterizing the earliest chromosomal alterations of pancreatic precursor neoplasms from individuals with a familial aggregation of pancreatic cancer may provide clues as to the loci of pancreatic cancer susceptibility genes. EXPERIMENTAL DESIGN: We used Illumina 370/660K SNP arrays to co...

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Hlavní autoři: Hong, Seung-Mo, Vincent, Audrey, Kanda, Mitsuro, Leclerc, Julie, Omura, Noriyuki, Borges, Michael, Klein, Alison P., Canto, Marcia Irene, Hruban, Ralph H., Goggins, Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3629843/
https://ncbi.nlm.nih.gov/pubmed/22723370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-1075
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