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Pharmacokinetic Interactions between Monoamine Oxidase A Inhibitor Harmaline and 5-Methoxy-N,N-Dimethyltryptamine, and the Impact of CYP2D6 Status

5-Methoxy-N,N-dimethyltryptamine (5-MeO-DMT or street name “5-MEO”) is a newer designer drug belonging to a group of naturally occurring indolealkylamines. Our recent study has demonstrated that coadministration of monoamine oxidase A (MAO-A) inhibitor harmaline (5 mg/kg) increases systemic exposure...

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Detalhes bibliográficos
Main Authors: Jiang, Xi-Ling, Shen, Hong-Wu, Mager, Donald E., Yu, Ai-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3629804/
https://ncbi.nlm.nih.gov/pubmed/23393220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.112.050724
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