Tau acts as an independent genetic risk factor in pathologically proven PD

MAPT has been repeatedly linked with Parkinson's disease (PD) in association studies. Although tau deposition may be seen in PD, its relevance to the pathogenesis of the condition remains unclear. The presence of tau-positive inclusions is, however, the defining feature of progressive supranucl...

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Hoofdauteurs: Charlesworth, Gavin, Gandhi, Sonia, Bras, Jose M., Barker, Roger A., Burn, David J., Chinnery, Patrick F., Gentleman, Stephen M., Guerreiro, Rita, Hardy, John, Holton, Janice L., Lees, Andrew, Morrison, Karen, Sheerin, Una-Marie, Williams, Nigel, Morris, Huw, Revesz, Tamas, Wood, Nicholas W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2012
Onderwerpen:
Genetic Reports Abstract
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3629571/
https://ncbi.nlm.nih.gov/pubmed/22221882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2011.11.001
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