Tau acts as an independent genetic risk factor in pathologically proven PD

MAPT has been repeatedly linked with Parkinson's disease (PD) in association studies. Although tau deposition may be seen in PD, its relevance to the pathogenesis of the condition remains unclear. The presence of tau-positive inclusions is, however, the defining feature of progressive supranucl...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Charlesworth, Gavin, Gandhi, Sonia, Bras, Jose M., Barker, Roger A., Burn, David J., Chinnery, Patrick F., Gentleman, Stephen M., Guerreiro, Rita, Hardy, John, Holton, Janice L., Lees, Andrew, Morrison, Karen, Sheerin, Una-Marie, Williams, Nigel, Morris, Huw, Revesz, Tamas, Wood, Nicholas W.
Format: Artigo
Langue:Inglês
Publié: Elsevier 2012
Sujets:
Genetic Reports Abstract
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3629571/
https://ncbi.nlm.nih.gov/pubmed/22221882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2011.11.001
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