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Reinforcing Effects Of Compounds Lacking Intrinsic Efficacy At α1 Subunit-Containing GABA(A) Receptor Subtypes in Midazolam- But Not Cocaine-Experienced Rhesus Monkeys

Benzodiazepines are prescribed widely but their utility is limited by unwanted side effects, including abuse potential. The mechanisms underlying the abuse-related effects of benzodiazepines are not well understood, although α1 subunit-containing GABA(A) receptors have been proposed to have a critic...

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Detalhes bibliográficos
Principais autores: Shinday, Nina M, Sawyer, Eileen K, Fischer, Bradford D, Platt, Donna M, Licata, Stephanie C, Atack, John R, Dawson, Gerard R, Reynolds, David S, Rowlett, James K
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3629390/
https://ncbi.nlm.nih.gov/pubmed/23303046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2012.265
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