A dominant negative mutation of the alpha retinoic acid receptor gene in a retinoic acid-nonresponsive embryonal carcinoma cell.

Pluripotential embryonal carcinoma cells such as those of the P19 line differentiate when exposed to retinoic acid (RA). The RAC65 cell line is a mutant clone of P19 cells selected to be RA nonresponsive. RAC65 cells carry a rearrangement affecting one of the genes encoding a nuclear retinoic acid r...

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Publié dans:	Mol Cell Biol
Auteurs principaux:	Pratt, M A, Kralova, J, McBurney, M W
Format:	Artigo
Langue:	Inglês
Publié:	Taylor & Francis 1990
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362921/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2174108/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.10.12.6445-6453.1990
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