Knockdown of FRAT1 Expression by RNA Interference Inhibits Human Glioblastoma Cell Growth, Migration and Invasion

BACKGROUND: FRAT1 positively regulates the Wnt/β-catenin signaling pathway by inhibiting GSK-3-mediated phosphorylation of β-catenin. It was originally characterized as a protein frequently rearranged in advanced T cell lymphoma, but has recently also been identified as a proto-oncogene involved in...

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Bibliografische gegevens
Hoofdauteurs: Guo, Geng, Kuai, Dong, Cai, Sang, Xue, Naizhao, Liu, Yueting, Hao, Jiehe, Fan, Yimin, Jin, Ji, Mao, Xinggang, Liu, Bolin, Zhong, Chengliang, Zhang, Xiang, Yue, Yi, Liu, Xiaodong, Ma, Ning, Guo, Yuhong
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2013
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3629175/
https://ncbi.nlm.nih.gov/pubmed/23613813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061206
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