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Overexpression of HIF-1α indicates a poor prognosis in tongue carcinoma and may be associated with tumour metastasis
Expression of the transcription factor hypoxiainducible factor 1 (HIF-1) plays a key role in cellular adaptation to hypoxia, particularly in relation to tumour angiogenesis. Expression of the HIF-1α subunit is responsive to changes in oxygen levels. Overexpression of HIF-1α has been reported to be a...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
D.A. Spandidos
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3629117/ https://ncbi.nlm.nih.gov/pubmed/23599780 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2013.1185 |
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