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Activation of octamer-containing promoters by either octamer-binding transcription factor 1 (OTF-1) or OTF-2 and requirement of an additional B-cell-specific component for optimal transcription of immunoglobulin promoters.

Several distinct octamer-binding transcription factors (OTFs) interact with the sequence ATTTGCAT (the octamer motif), which acts as a transcription regulatory element for a variety of differentially controlled genes. The ubiquitous OTF-1 plays a role in expression of the cell cycle-regulated histon...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Principais autores: Pierani, A, Heguy, A, Fujii, H, Roeder, R G
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362895/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2123291/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.10.12.6204-6215.1990
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