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Analysis of innate and acquired resistance to anti-CD20 antibodies in malignant and nonmalignant B cells

The anti-CD20 monoclonal antibody, rituximab, provides a significant therapeutic benefit for patients with B-cell disorders. However, response to therapy varies and relapses are common, so an understanding of both inherited and acquired rituximab resistance is needed. In order to identify mechanisms...

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Autori principali: Small, George W., McLeod, Howard L., Richards, Kristy L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: PeerJ Inc. 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628892/
https://ncbi.nlm.nih.gov/pubmed/23638367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.31
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