The Relationship between RTS,S Vaccine-Induced Antibodies, CD4(+) T Cell Responses and Protection against Plasmodium falciparum Infection

Vaccination with the pre-erythrocytic malaria vaccine RTS,S induces high levels of antibodies and CD4(+) T cells specific for the circumsporozoite protein (CSP). Using a biologically-motivated mathematical model of sporozoite infection fitted to data from malaria-naive adults vaccinated with RTS,S a...

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Hlavní autoři: White, Michael T., Bejon, Philip, Olotu, Ally, Griffin, Jamie T., Riley, Eleanor M., Kester, Kent E., Ockenhouse, Christian F., Ghani, Azra C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628884/
https://ncbi.nlm.nih.gov/pubmed/23613845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061395
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