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Visualizing group II intron catalysis through the stages of splicing
Group II introns are self-splicing ribozymes that share a reaction mechanism and a common ancestor with the eukaryotic spliceosome, thereby providing a model system for understanding the chemistry of pre-mRNA splicing. Here we report fourteen crystal structures of a group II intron at different stag...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3628766/ https://ncbi.nlm.nih.gov/pubmed/23101623 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.09.033 |
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