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Visualizing group II intron catalysis through the stages of splicing

Group II introns are self-splicing ribozymes that share a reaction mechanism and a common ancestor with the eukaryotic spliceosome, thereby providing a model system for understanding the chemistry of pre-mRNA splicing. Here we report fourteen crystal structures of a group II intron at different stag...

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Detalhes bibliográficos
Main Authors: Marcia, Marco, Pyle, Anna Marie
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628766/
https://ncbi.nlm.nih.gov/pubmed/23101623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.09.033
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