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Potential molecular mechanisms for decreased synaptic glutamate release in dysbindin-1 mutant mice

Behavioral genetic studies of humans have associated variation in the DTNBP1 gene with schizophrenia and its cognitive deficit phenotypes. The protein encoded by DTNBP1, dysbindin-1, is expressed in forebrain neurons where it interacts with proteins mediating vesicular trafficking and exocytosis. It...

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Detalhes bibliográficos
Main Authors: Saggu, Shalini, Cannon, Tyrone D., Jentsch, J. David, Lavin, Antonieta
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628687/
https://ncbi.nlm.nih.gov/pubmed/23473812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.schres.2013.01.037
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