Persistent strong anti-HLA antibody at high titer is complement binding and associated with increased risk of antibody-mediated rejection in heart transplant recipients

BACKGROUND: Sensitized heart transplant candidates are evaluated for donor-specific anti-HLA IgG antibody (DSA) by Luminex single-antigen bead (SAB) testing (SAB-IgG) to determine donor suitability and help predict a positive complement-dependent cytotoxicity crossmatch (CDC-XM) by virtual crossmatc...

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Main Authors: Zeevi, Adriana, Lunz, John, Feingold, Brian, Shullo, Michael, Bermudez, Christian, Teuteberg, Jeffery, Webber, Steven
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628631/
https://ncbi.nlm.nih.gov/pubmed/23142561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.healun.2012.09.021
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