A critical role for suppressors of cytokine signaling 3 in regulating LPS-induced transcriptional activation of matrix metalloproteinase-13 in osteoblasts

Suppressor of cytokine signaling 3 (SOCS3) is a key regulator of cytokine signaling in macrophages and T cells. Although SOCS3 seems to contribute to the balance between the pro-inflammatory actions of IL-6 family of cytokines and anti-inflammatory signaling of IL-10 by negatively regulating gp130/J...

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Detalles Bibliográficos
Autores principales: Gao, Anqi, Kantarci, Alpdogan, Herrera, Bruno Schneider, Gao, Hongwei, Van Dyke, Thomas E.
Formato: Artigo
Lenguaje:Inglês
Publicado: PeerJ Inc. 2013
Materias:
Biochemistry
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628613/
https://ncbi.nlm.nih.gov/pubmed/23638389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.51
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