Paraquat Modulates Alternative Pre-mRNA Splicing by Modifying the Intracellular Distribution of SRPK2

Paraquat (PQ) is a neurotoxic herbicide that induces superoxide formation. Although it is known that its toxic properties are linked to ROS production, the cellular response to PQ is still poorly understood. We reported previously that treatment with PQ induced genome-wide changes in pre-mRNA splici...

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Hauptverfasser: Vivarelli, Silvia, Lenzken, Silvia C., Ruepp, Marc-David, Ranzini, Francesco, Maffioletti, Andrea, Alvarez, Reinaldo, Mühlemann, Oliver, Barabino, Silvia M. L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628584/
https://ncbi.nlm.nih.gov/pubmed/23613995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061980
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