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Nanodisc-solubilized membrane protein library reflects the membrane proteome

The isolation and identification of unknown membrane proteins offers the prospect of discovering new pharmaceutical targets and identifying key biochemical receptors. However, interactions between membrane protein targets and soluble ligands are difficult to study in vitro due to the insolubility of...

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Hlavní autoři: Marty, Michael T., Wilcox, Kyle C., Klein, William L., Sligar, Stephen G.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628400/
https://ncbi.nlm.nih.gov/pubmed/23400332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-013-6790-8
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