Serotonin Transporter and Receptor Genes Significantly Impact Nicotine Dependence through Genetic Interactions in both European American and African American Smokers

BACKGROUND: Pharmacologic studies implicate a significant role of genes encoding the serotonin transporter (SLC6A4) and the 5-HT(3AB) subunits HTR3A and HTR3B in nicotine dependence (ND). However, whether they are involved in ND remains largely unknown. METHODS: Here, we examined the impact of varia...

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Hlavní autoři: Yang, Zhongli, Seneviratne, Chamindi, Wang, Shaolin, Ma, Jennie Z., Payne, Thomas J., Wang, Jundong, Li, Ming D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628090/
https://ncbi.nlm.nih.gov/pubmed/23290502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drugalcdep.2012.12.007
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