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Imputation across genotyping arrays for genome-wide association studies: assessment of bias and a correction strategy
A great promise of publicly sharing genome-wide association data is the potential to create composite sets of controls. However, studies often use different genotyping arrays, and imputation to a common set of SNPs has shown substantial bias: a problem which has no broadly applicable solution. Based...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3628082/ https://ncbi.nlm.nih.gov/pubmed/23334152 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-013-1266-7 |
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