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A secure distributed logistic regression protocol for the detection of rare adverse drug events

BACKGROUND: There is limited capacity to assess the comparative risks of medications after they enter the market. For rare adverse events, the pooling of data from multiple sources is necessary to have the power and sufficient population heterogeneity to detect differences in safety and effectivenes...

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Main Authors: El Emam, Khaled, Samet, Saeed, Arbuckle, Luk, Tamblyn, Robyn, Earle, Craig, Kantarcioglu, Murat
Format: Artigo
Jezik:Inglês
Izdano: BMJ Group 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628043/
https://ncbi.nlm.nih.gov/pubmed/22871397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/amiajnl-2011-000735
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