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The Decline in Pulsatile GnRH Release, as Reflected by Circulating LH Concentrations, During the Infant-Juvenile Transition in the Agonadal Male Rhesus Monkey (Macaca mulatta) Is Associated With a Reduction in Kisspeptin Content of KNDy Neurons of the Arcuate Nucleus in the Hypothalamus

Puberty in primates is timed by 2 hypothalamic events: during late infancy a decline in pulsatile GnRH release occurs, leading to a hypogonadotropic state that maintains quiescence of the prepubertal gonad; and in late juvenile development, pulsatile GnRH release is reactivated and puberty initiated...

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Autors principals: Ramaswamy, Suresh, Dwarki, Karthik, Ali, Barkat, Gibbs, Robert B., Plant, Tony M.
Format: Artigo
Idioma:Inglês
Publicat: Endocrine Society 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628021/
https://ncbi.nlm.nih.gov/pubmed/23525220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2012-2154
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