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Status epilepticus enhances tonic GABA currents and depolarizes GABA reversal potential in dentate fast-spiking basket cells

Temporal lobe epilepsy is associated with loss of interneurons and inhibitory dysfunction in the dentate gyrus. While status epilepticus (SE) leads to changes in granule cell inhibition, whether dentate basket cells critical for regulating granule cell feedforward and feedback inhibition express ton...

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Main Authors: Yu, Jiandong, Proddutur, Archana, Elgammal, Fatima S., Ito, Takahiro, Santhakumar, Vijayalakshmi
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628014/
https://ncbi.nlm.nih.gov/pubmed/23324316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00891.2012
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