Novel Split-Luciferase-Based Genetically Encoded Biosensors for Noninvasive Visualization of Rho GTPases

Rho family GTPases are critical regulators of many important cellular processes and the dysregulation of their activities is implicated in a variety of human diseases including oncogenesis and propagation of malignancy. The traditional methods, such as “pull-down” or two-hybrid procedures, are poorl...

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Detalhes bibliográficos
Main Authors: Leng, Weibing, Pang, Xiaohui, Xia, Hongwei, Li, Mingxing, Chen, Liu, Tang, Qiulin, Yuan, Dandan, Li, Ronghui, Li, Libo, Gao, Fabao, Bi, Feng
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3627919/
https://ncbi.nlm.nih.gov/pubmed/23614039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0062230
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