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Major histocompatibility complex class I genes in murine fibrosarcoma IC9 are down regulated at the level of the chromatin structure.

The fibrosarcoma IC9 is deficient in the expression of the major histocompatibility complex class I genes Kb, Kk, and Dk and expresses only the Db molecule. Because class I deficiency may enable tumor cells to escape the immune response by cytotoxic T lymphocytes, we investigated why the class I gen...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Maschek, U, Pülm, W, Segal, S, Hämmerling, G J
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362789/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2506438/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.9.7.3136
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