Prophylactic Perioperative Sodium Bicarbonate to Prevent Acute Kidney Injury Following Open Heart Surgery: A Multicenter Double-Blinded Randomized Controlled Trial

BACKGROUND: Preliminary evidence suggests a nephroprotective effect of urinary alkalinization in patients at risk of acute kidney injury. In this study, we tested whether prophylactic bicarbonate-based infusion reduces the incidence of acute kidney injury and tubular damage in patients undergoing op...

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Главные авторы: Haase, Michael, Haase-Fielitz, Anja, Plass, Michael, Kuppe, Hermann, Hetzer, Roland, Hannon, Claire, Murray, Patrick T., Bailey, Michael J., Bellomo, Rinaldo, Bagshaw, Sean M.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2013
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3627643/
https://ncbi.nlm.nih.gov/pubmed/23610561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.1001426
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