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DNA methylation patterns associated with asparagine synthetase expression in asparagine-overproducing and -auxotrophic cells.

In Chinese hamster ovary cells, the gene for asparagine synthetase, which spans 20 kilobase pairs, was found to contain a cluster of potential sites for CpG methylation in a 1-kilobase-pair region surrounding the first exon. Fourteen of the sites that could be assayed for methylation by MspI-HpaII d...

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Publicat a:Mol Cell Biol
Autors principals: Andrulis, I L, Barrett, M T
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1989
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362759/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2571077/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.9.7.2922-2927.1989
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