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High-resolution nucleosome mapping of targeted regions using BAC-based enrichment
We report a target enrichment method to map nucleosomes of large genomes at unprecedented coverage and resolution by deeply sequencing locus-specific mononucleosomal DNA enriched via hybridization with bacterial artificial chromosomes. We achieved ∼10 000-fold enrichment of specific loci, which enab...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3627574/ https://ncbi.nlm.nih.gov/pubmed/23413004 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt081 |
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