Llwytho...
A critical role for the non-coding 5S rRNA in regulating Mdmx stability
Both p53 and Mdmx are ubiquitinated and degraded by the same E3 ligase Mdm2; interestingly, however, while p53 is rapidly degraded by Mdm2, Mdmx is a stable protein in most of cancer cells. Thus, the mechanism by which Mdmx is degraded by Mdm2 needs further elucidation. Here, we identified the nonco...
Wedi'i Gadw mewn:
Prif Awduron: | , |
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Fformat: | Artigo |
Iaith: | Inglês |
Cyhoeddwyd: |
2011
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Pynciau: | |
Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3627499/ https://ncbi.nlm.nih.gov/pubmed/21925390 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.08.020 |
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