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In vitro and in vivo evaluation of a sublingual fentanyl wafer formulation

BACKGROUND: The objective of this study was to prepare a novel fentanyl wafer formulation by a freeze-drying method, and to evaluate its in vitro and in vivo release characteristics, including its bioavailability via the sublingual route. METHODS: The wafer formulation was prepared by freeze-drying...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lim, Stephen CB, Paech, Michael J, Sunderland, Bruce, Liu, Yandi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3627472/
https://ncbi.nlm.nih.gov/pubmed/23596347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S42619
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