Bone marrow–derived MCP1 required for experimental aortic aneurysm formation and smooth muscle phenotypic modulation

OBJECTIVES: This study tested the hypothesis that monocyte chemotactic protein 1 (MCP1) is required for abdominal aortic aneurysm (AAA) and smooth muscle phenotypic modulation in a mouse elastase perfusion model. METHODS: Infrarenal aortas of C57BL/6 (wild type [WT]) and MCP1 knockout (KO) mice were...

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Detalhes bibliográficos
Main Authors: Moehle, Christopher W., Bhamidipati, Castigliano M., Alexander, Matthew R., Mehta, Gaurav S., Irvine, James N., Salmon, Morgan, Upchurch, Gilbert R., Kron, Irving L., Owens, Gary K., Ailawadi, Gorav
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3627218/
https://ncbi.nlm.nih.gov/pubmed/21996300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtcvs.2011.07.053
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