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Chromosomal evolution of Escherichia coli for the efficient production of lycopene

BACKGROUND: Plasmid-based overexpression of genes has been the principal strategy for metabolic engineering. However, for biotechnological applications, plasmid-based expression systems are not suitable because of genetic instability, and the requirement for constant selective pressure to ensure pla...

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Detalhes bibliográficos
Main Authors: Chen, Yun-Yan, Shen, Hong-Jie, Cui, Yan-Yan, Chen, Shang-Guang, Weng, Zhi-Ming, Zhao, Ming, Liu, Jian-Zhong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3626847/
https://ncbi.nlm.nih.gov/pubmed/23356604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-13-6
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