Evidence of recent natural selection on the Southeast Asian deletion (--(SEA)) causing α-thalassemia in South China

BACKGROUND: The Southeast Asian deletion (--(SEA)) is the most commonly observed mutation among diverse α-thalassemia alleles in Southeast Asia and South China. It is generally argued that mutation --(SEA), like other variants causing hemoglobin disorders, is associated with protection against malar...

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Hlavní autoři: Qiu, Qin-Wei, Wu, Dong-Dong, Yu, Li-Hua, Yan, Ti-Zhen, Zhang, Wen, Li, Zhe-Tao, Liu, Yan-Hui, Zhang, Ya-Ping, Xu, Xiang-Min
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2013
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3626844/
https://ncbi.nlm.nih.gov/pubmed/23497175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-13-63
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