Src-mediated morphology transition of lung cancer cells in three-dimensional organotypic culture

A fribotic tumor microenvironment promotes progression of cancer. In this study, we utilize a reconstituted basement membrane mimics Matrigel based three-dimensional organotypic culture (rBM 3-D) to investigate the mechanisms that mediate the tumor promoting effects of the fibrogenic mediators TGF-β...

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Detalhes bibliográficos
Main Authors: Nguyen, Hong T, Zhuang, Yan, Sun, Lichun, Kantrow, Steven P, Kolls, Jay K, You, Zongbing, Zhuo, Ying, Shan, Bin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Primary Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3626791/
https://ncbi.nlm.nih.gov/pubmed/23409704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-13-16
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