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Disruption of the Sec24d Gene Results in Early Embryonic Lethality in the Mouse
Transport of newly synthesized proteins from the endoplasmic reticulum (ER) to the Golgi is mediated by the coat protein complex COPII. The inner coat of COPII is assembled from heterodimers of SEC23 and SEC24. Though mice with mutations in one of the four Sec24 paralogs, Sec24b, exhibit a neural tu...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Public Library of Science
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3626607/ https://ncbi.nlm.nih.gov/pubmed/23596517 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061114 |
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