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Hybrid Approach for Predicting Coreceptor Used by HIV-1 from Its V3 Loop Amino Acid Sequence
BACKGROUND: HIV-1 infects the host cell by interacting with the primary receptor CD4 and a coreceptor CCR5 or CXCR4. Maraviroc, a CCR5 antagonist binds to CCR5 receptor. Thus, it is important to identify the coreceptor used by the HIV strains dominating in the patient. In past, a number of experimen...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
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Public Library of Science
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3626595/ https://ncbi.nlm.nih.gov/pubmed/23596523 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061437 |
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