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The regulated production of mu m and mu s mRNA is dependent on the relative efficiencies of mu s poly(A) site usage and the c mu 4-to-M1 splice.

The relative abundance of the mRNAs encoding the membrane (mu m) and secreted (mu s) forms of immunoglobulin mu heavy chain is regulated during B-cell maturation by a change in the mode of RNA processing. Current models to explain this regulation involve either competition between cleavage-polyadeny...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Principais autores: Peterson, M L, Perry, R P
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362650/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2565533/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.9.2.726-738.1989
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