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Physical linkage of mouse lambda genes by pulsed-field gel electrophoresis suggests that the rearrangement process favors proximate target sequences.

The first complete map of a mammalian immunoglobulin gene locus is presented. Mouse lambda genes were mapped by pulsed-field gel electrophoresis. The gene order is V2-Vx-C2-C4-V1-C3-C1. The distance between V2 or Vx and the C2-C4 cluster is 74 or 55 kilobases (kb), respectively, whereas that between...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Principais autores: Storb, U, Haasch, D, Arp, B, Sanchez, P, Cazenave, P A, Miller, J
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362648/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2710121/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.9.2.711-718.1989
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