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The bcl-2 candidate proto-oncogene product is a 24-kilodalton integral-membrane protein highly expressed in lymphoid cell lines and lymphomas carrying the t(14;18) translocation.

We have identified a 24-kilodalton protein that is the product of the human bcl-2 gene, implicated as an oncogene because of its presence at the site of t(14;18) translocation breakpoints. The Bcl-2 protein was detected by specific, highly sensitive rabbit antibodies and was shown to be present in a...

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Bibliografiset tiedot
Julkaisussa:Mol Cell Biol
Päätekijät: Chen-Levy, Z, Nourse, J, Cleary, M L
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Taylor & Francis 1989
Aiheet:
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362647/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2651903/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.9.2.701
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