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Adaptive Regulation Maintains Posttetanic Potentiation at Cerebellar Granule Cell Synapses in the Absence of Calcium-Dependent PKC

Posttetanic potentiation (PTP) is a transient, calcium-dependent increase in the efficacy of synaptic transmission following elevated presynaptic activity. The calcium-dependent protein kinase C (PKC(Ca)) isoforms PKCα and PKCβ mediate PTP at the calyx of Held synapse, with PKCβ contributing signifi...

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Autori principali: Fioravante, Diasynou, Myoga, Michael H., Leitges, Michael, Regehr, Wade G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3626454/
https://ncbi.nlm.nih.gov/pubmed/22993418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0683-12.2012
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