Differential regulation of microRNA-146a and microRNA-146b-5p in human retinal pigment epithelial cells by interleukin-1β, tumor necrosis factor-α, and interferon-γ

PURPOSE: The inflammatory response of the retinal pigment epithelium (RPE) is implicated in the pathogenesis of age-related macular degeneration. The microRNAs miR-146a and miR-146b-5p can regulate the inflammatory process by attenuating cytokine signaling via the nuclear factor-κB pathway. The aim...

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Principais autores: Kutty, R. Krishnan, Nagineni, Chandrasekharam N., Samuel, William, Vijayasarathy, Camasamudram, Jaworski, Cynthia, Duncan, Todd, Cameron, Jennifer E., Flemington, Erik K., Hooks, John J., Redmond, T. Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Vision 2013
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3626297/
https://ncbi.nlm.nih.gov/pubmed/23592910
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