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Characterization of the Acyl-Adenylate Linked Metabolite of Mefenamic Acid

Mefenamic acid, (MFA), a carboxylic acid-containing nonsteroidal anti-inflammatory drug (NSAID), is metabolized into the chemically-reactive conjugates MFA-1-O-acyl-glucuronide (MFA-1-O-G) and MFA-S-acyl-CoA (MFA-CoA), which are both implicated in the formation of MFA-S-acyl-glutathione (MFA-GSH) co...

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Detalhes bibliográficos
Main Authors: Horng, Howard, Benet, Leslie Z.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3626286/
https://ncbi.nlm.nih.gov/pubmed/23402341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx300520j
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