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High-resolution mapping of replication fork movement through the amplified dihydrofolate reductase domain in CHO cells by in-gel renaturation analysis.

Utilizing an in vivo labeling method on synchronized cultures, we have previously defined a 28-kilobase (kb) replication initiation locus in the amplified dihydrofolate reductase domain of a methotrexate-resistant Chinese hamster ovary cell line (CHOC 400) (N. H. Heintz and J. L. Hamlin, Proc. Natl....

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Bibliografske podrobnosti
izdano v:Mol Cell Biol
Principais autores: Leu, T H, Hamlin, J L
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 1989
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362628/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2710115/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.9.2.523-531.1989
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