Single Chain Epidermal Growth Factor Receptor Antibody Conjugated Nanoparticles for in vivo Tumor Targeting and Imaging

Epidermal growth factor receptor (EGFR) targeted nanoparticle are developed by conjugating a single-chain anti-EGFR antibody (ScFvEGFR) to surface functionalized quantum dots (QDs) or magnetic iron oxide (IO) nanoparticles. The results show that ScFvEGFR can be successfully conjugated to the nanopar...

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Detalhes bibliográficos
Main Authors: Yang, Lily, Mao, Hui, Wang, Y. Andrew, Cao, Zehong, Peng, Xianghong, Wang, Xiaoxia, Duan, Hongwei, Ni, Chunchun, Yuan, Qingan, Adams, Gregory, Smith, Mark Q., Wood, William C., Gao, Xiaohu, Nie, Shuming
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3626261/
https://ncbi.nlm.nih.gov/pubmed/19089838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/smll.200800714
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