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Virus-specific CD4(+) memory phenotype T cells are abundant in unexposed adults
While T cell memory is generally thought to require direct antigen exposure, we find an abundance of memory phenotype cells (20–90%, averaging over 50%) of CD4(+) T cells specific for viral antigens in adults that have never been infected. These cells express the appropriate memory markers and genes...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3626102/ https://ncbi.nlm.nih.gov/pubmed/23395677 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2012.10.021 |
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