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Induction of tumor promotor-inducible genes in murine 3T3 cell lines and tetradecanoyl phorbol acetate-nonproliferative 3T3 variants can occur through protein kinase C-dependent and -independent pathways.

We isolated a group of genes that are rapidly and transiently induced in 3T3 cells by tetradecanoyl phorbol acetate (TPA). These genes are called TIS genes (for TPA-inducible sequences). Epidermal growth factor (EGF), fibroblast growth factor (FGF), and TPA activated TIS gene expression with similar...

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Publicat a:Mol Cell Biol
Autors principals: Lim, R W, Varnum, B C, O'Brien, T G, Herschman, H R
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1989
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362599/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2471069/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.9.4.1790
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