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Mutagenesis of the rat insulin II 5'-flanking region defines sequences important for expression in HIT cells.

To define the cis-acting elements important for rat insulin II gene expression, we analyzed the effects of 5' deletions and linker-scanning mutations on the expression of a rat insulin II reporter gene in an insulinoma cell line (HIT). The reporter gene contained 448 base pairs of 5'-flank...

詳細記述

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書誌詳細
主要な著者: Crowe, D T, Tsai, M J
フォーマット: Artigo
言語:Inglês
出版事項: 1989
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC362598/
https://ncbi.nlm.nih.gov/pubmed/2657405
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